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The medication works by mimicking the incretin hormone GLP-1, which enhances glucose-dependent insulin secretion, suppresses glucagon release, and slows gastric emptying
If you have severe side effects from semaglutide, talk to your healthcare provider before you stop the medication
Understanding these stages prevents the most common mistake new users make, which is assuming the medication is not effective simply because they do not feel different yet
Global NASH Council, American Association for the Study of Liver Diseases (AASLD), EASL | The Home of Hepatology, Canadian Association for the Study of the Liver, European Liver Patients' Association - ELPA, Global Liver Institute, Priti Chawla, Obesity Matters, American Diabetes Association Fatty Liver Alliances Post GLP-1 receptor agonists (GLP-1RAs) show promise in managing metabolic dysfunction-associated steatotic liver disease (MASLD) by reducing hepatic steatosis, resolving MASH, and mitigating fibrosis progression
Last reviewed: June 17, 2026 Last updated: June 17, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations
