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326,327 Importantly, zinc may inhibit neuronal NMDA glutamate receptors, which are dysregulated in those with depression, and raise BDNF levels, which can promote neuroplasticity

36,38,39 Compared to oral administration, whereby under 10% actually enters the blood stream, 52 orobuccal administration leads to over 80% absorption directly into the systemic circulation

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Pharmacogenetics 8 : 91100

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