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Up to 21 days at room temperature (86 F / 30 C) after first removal from the refrigerator

Metformin commonly causes gastrointestinal side effects including stomach pain, nausea, bloating, and diarrhoea, particularly when first started or when the dose is increased

Complementary evidence comes from Wang et al., who used cadmium-induced testicular toxicity model in male rats and showed that quercetin mitigated oxidative damage in the testes by evaluating SOD, GPx, CAT and GSH, lowering MDA levels, and reducing cadmium accumulation

doi: 10.1007/BF02257619 40

Diabetologia 2022

Spreading protein across 5-6 meals, with 30-50 grams per feeding, ensures consistent amino acid availability for muscle protein synthesis