The Endocrine Society's clinical practice guideline on GH deficiency states: "GH therapy is contraindicated in patients with active malignancy" [10]
2 mM dl-propargylglycine (PPG, SigmaAldrich), 0.2 mM l-homocysteine (Hcy, SigmaAldrich), or 0.5 mM l-methionine (Met, Research Products International, Inc) was added as indicated
Intramuscular (IM) B12 Administration Protocol For those with vitamin B12 deficiency, intramuscular injections are a good treatment
PMID 20625493
The idea with BHRT is that it helps your body regulate itself by replacing the hormones it needs to function properly the hormones your body produces naturally, or at least the hormones its supposed to produce naturally
It also improves insulin sensitivity, which makes it a solid match for the metabolic effects of semaglutide or tirzepatide