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[3] Prolonged therapy can unmask or exacerbate benign prostatic hyperplasia, raise prostate-specific antigen, worsen untreated obstructive sleep apnoea and is associated in some observational studies with a small but controversial increase in cardiovascular events, underlining the necessity for baseline and periodic monitoring of PSA, lipids and cardiovascular risk factors
Accessed May 12, 2025
treatment form (oral or intramuscular hydroxocobalamin) depends on the underlying cause
Most complications can be treated successfully
Pregnancy and breastfeeding, unless specifically cleared by a physician due to unknown effects
observed in Nature Medicine , NNMT inhibition in adipose tissue produced favorable body composition changes without negatively impacting muscle mass (Kraus et al., Nature Medicine )
