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Recent meta-analyses grade it low certainty with no consistent overall increase (Liu 2025)
Hills AP, Arena R, Khunti K, et al
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The groups were matched for age, sex and race
[7] The replacement of NAD+, however, appears to support a number of other metabolic pathways via NAD+-dependent enzymes, according to research in animal models and humans (and/or samples and cell lines)
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