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Glutathione exists in two primary forms: the reduced form (GSH), characterized by a free sulfhydryl group (-SH) on its cysteine residue, and the oxidized form, glutathione disulfide (GSSG), which is formed when two GSH molecules are linked via a disulfide bond between their cysteine residues during redox reactions
Furthermore, the acute metabolic response to 5FU treatment is profound and facilitates tolerance
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On the other hand, autophagy leads to a significant decrease in intracellular GSH levels and vice versa 67
Role of phosphodiesterase-4 inhibitors in chronic obstructive pulmonary disease
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