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and sterol 27-hydroxylase ( Cyp27a1 ), which is the initial enzyme in the alternative pathway
Common issues reported in clinical studies include nausea, diarrhea, and mild gastrointestinal discomfort
Still within the reconstituted peptide stability window
Compliance credentials
Most standard antihistamines do not affect the efficacy of escitalopram, but some medicines such as cimetidine (an older antihistamine and antacid) inhibit the CYP2C19 enzyme that metabolises escitalopram, potentially raising its plasma levels and increasing the risk of side effects
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