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PMID: 18046908
This peroxidation occurs via two major pathways: the enzymatic pathway, mediated by lipoxygenases (LOXs), cytochrome P450 oxidoreductase (POR), and NADPH oxidases (NOXs), promotes the generation of PUFA-PL-OOHs, leading to the accumulation of reactive aldehydes, ketones, and other toxic metabolites, ultimately disrupting membrane integrity and triggering ferroptosis (Maheshwari, 2023)
10.1016/j.theriogenology.2020.01.045 56
En pacientes con f ibromialgia, este tipo de formulacin podra contribuir a una disminucin progresiva del estrs oxidativo, fatiga y dolor muscular, aunque la evidencia clnica directa an es limitada
Homocysteine Metabolism as the Target for Predictive Medical Approach, Disease Prevention, Prognosis, and Treatments Tailored to the Person. The EPMA Journal, vol