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In terms of changes in fat mass, the decreases in right arm, left arm, android, and gynoid were all greater than those in the right leg and left leg, a difference that may be related to variations in baseline fat mass across regions
Both are effective for weight loss, but Mounjaro (tirzepatide) has shown slightly greater average weight reduction in clinical trials compared to Wegovy (semaglutide)
Regular check-ins are essential as they allow for interaction between the patient and provider to discuss progress and if any side effects are occurring
Research published in the New England Journal of Medicine and subsequent body composition sub-analyses from the STEP trials have begun to quantify this more precisely
Diabetes Obes Metab 27(2):806815 Simms-Williams N, Treves N, Yin H, Lu S, Yu O, Pradhan R et al (2024) Effect of combination treatment with glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors on incidence of cardiovascular and serious renal events: population-based cohort study
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