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These indicate either excessive dosing or sensitivity to the peptide
It has been observed that the increase of GSH levels has a cytoprotective effect
Conclusions To summarize, more than 19 years after exenatide's approval, newer once-weekly GLP-1 medicines like semaglutide and tirzepatide have shown long-term efficacy and safety for type 2 diabetes and obesity
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The dosing conditions, schedule and washout period in both studies ensured there was no effect of food or drugdrug interaction between the two drugs evaluated in each study
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