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Conflict of interest BG has served as a consultant for AstraZeneca, Boehringer Ingelheim, Bristol-Myers Squibb, Merck (MSD) and Novartis as manufacturers of DPP-4 inhibitors and has received honoraria from these companies for lectures

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This causes your bones to rub against one another, resulting in irreversible damage to your joints and pain and tenderness to the affected areas

These effects are often more noticeable when starting treatment or increasing dosage, and may improve as the body adjusts

Furthermore, IR in the liver and adipose tissue has been regarded as a crucial driver of NASH morbidity and mortality (120)

The chart below is an educational example based on commonly discussed Retatrutide dose levels in research settings