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Starting metformin extended-release and titrating GLP-1 therapy slowly (typically over 46 weeks) minimizes tolerability issues and improves adherence
This dual action enhances insulin secretion, lowers glucagon levels, and slows gastric emptying, resulting in reduced appetite and increased feelings of fullness
Their findings havent been published yet in a peer-reviewed journal
Research-use disclaimer: This article is an educational and research reference only
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