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(2014, July 31)
The clinical trials that established the safety and efficacy profiles for semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) included older adults, but in numbers that were not sufficient to characterize body composition changes, functional outcomes, or long-term musculoskeletal effects specifically in adults over 65 or 75
Early research, mostly animal and laboratory studies, suggests BPC-157 may support kidney repair by reducing fibrosis, improving blood flow, and encouraging new blood-vessel growth
A greater proportion of participants in the treatment group were White (71% vs 47%)
In March 2026, the FDA approved a higher strength of Semaglutide injection, 7.2 mg, sold under Wegovy HD, for certain adults who need additional weight reduction
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