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however, increased ischemic stroke risk in this context has been observed as well (Chen 2020

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We observe a hydrophobic extracellular gate directly above the substrate-binding site, similar to that seen in OCT1, where residues of gating helices TM1 and TM7 pack together in both the occluded and inward conformations (e.g

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[Effect of l-carnitine on the expression of glycine conjugates in rats in experimental [PMID: 9541994] Laboratory literature summary: [Effect of l-carnitine on the expression of glycine conjugates in rats in experimental B2-hypovitaminosis]

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