Similarly, the substudy of the obesity phase 2 trial showed clear promise for retatrutide in the treatment of MASLD [47], and through its GCG receptor agonism, retatrutide may offer benefits beyond WL, through weight-independent metabolic effects at the liver [40]
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Therefore, regulatory factors that could reduce lipid deposition in fish, especially during HFD feeding, have attracted increased research attention
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These studies have suggested that there may be mechanisms beyond antioxidant activities playing a neuroprotective role [118]
Side-effect profile is similar to GLP-1 agonists