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This multi-receptor approach produces more powerful metabolic effects than current dual agonists like tirzepatide (Mounjaro/Zepbound)
24.2% at 48 weeks in Phase 2 Tirzepatide : Up to 20.9% body weight reduction (SURMOUNT trials) Advantage : Retatrutide Regulatory Status# Retatrutide : Phase 1-3 clinical trials
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Note that semaglutide treatment works best as part of an all-encompassing approach
Handling dose escalation side effects The transition periods, especially from 2mg to 4mg and from 4mg to 8mg, are where most side effects occur
Continued research will assist in dosing safely and better for more individuals
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