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Stress meets genetics: Genetics loads the pistol, while oxidative stress fires the shot
The constitutive heterodimeric Rag GTPases, which consist of GTP-loaded RagA/B and GDP-loaded RagC/D, promote the translocation of mTORC1 to the lysosome, where it physically interacts with and then is activated by Rheb (Wolfson and Sabatini, 2017)
You should check your blood glucose levels as advised by your diabetes team, watching particularly for patterns of low blood glucose (below 4 mmol/L)
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10.1111/febs.13412 40 KempurajD.ThangavelR.NatteruP
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