It is a signaling molecule that coordinates multiple repair and remodeling processes at the cellular level
"Vitamin B 12 deficiency"
DNA synthesis: B12 is necessary for making and repairing DNA, which is essential for healthy cell growth and replication
Despite wide dose ranges tested (6 g/kg to 20 mg/kg), multiple administration routes (intramuscular, intraperitoneal, intravenous, oral), and varied dosing frequencies across numerous animal models, no acute lethal dose has been identified
A study with 312 patients found that using a ceramide-containing routine for 4 weeks reduced the severity of atopic dermatitis by over 61%
Disruption of these processes can result in increased BMI, generalized and abdominal obesity, hypertension, dyslipidemia, type 2 diabetes, and CVD (13)