(PubMed) Mahmoud NN, Carothers AM, Grunberger D, et al
CPAP therapy can be cumbersome and uncomfortable, so recommendations for CPAP are generally reserved for patients who experience excessive daytime sleepiness, those with comorbid hypertension, and those for whom their sleep disruption affects their quality of life
It may also encourage collagen synthesis , which is vital for the integrity of muscles, tendons, and ligaments
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[1] [12] For most people, doses up to 2 mg (2000 micrograms) daily are unlikely to cause harm according to NHS guidance, as B12 is water-soluble and excess is typically excreted in urine
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