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Semaglutide has a half-life of approximately 7 days and should be discontinued at least 2 months (approximately 5 half-lives) before conception

Examine the cardiovascular and renal protective effects of GLP-1 receptor agonists while addressing practical considerations for implementation, including patient selection, adherence, and access challenges

Anaemia can be caused by several factors including inadequate intake or absorption of iron, vitamin B12, folate, copper and zinc

26 Experiments in pancreatic islets reveal that -arrestin limits the insulin response to GLP-1, but not GIP or tirzepatide, suggesting that the biased agonism and imbalance of tirzepatide toward the GIP receptor and its unique GLP-1 receptor signaling properties might be at the basis of its potent action

Targeting glp-1 receptor trafficking to improve agonist efficacy