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Studies, including the MASALA study on South Asian immigrants in America, highlight the particularly high susceptibility of South Asians to these conditions
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Its potential as a medicine was discovered in 1992 when researchers isolated exendin-4, a longer-lasting simulation of human GLP-1 produced in the saliva of the Gila monster
Some short-term studies in healthy older adults have been done with GHRH analogs like sermorelin or other secretagogues, and while they sometimes show increases in lean mass or decreases in fat mass, the improvements are modest and can be accompanied by side effects (e.g
Semaglutide (Ozempic, Wegovy, Rybelsus) is the most prescribed GLP-1 receptor agonist worldwide, with proven efficacy across diabetes, obesity, and cardiovascular outcomes
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