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Comparing these peptides helps researchers evaluate differences in mechanistic targets, signaling behavior, and experimental design considerations across similar preclinical research domains
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Br J Haematol 2020;190:e2657 11
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267 GAS6, secreted by stromal cells such as CAFs and macrophages, binds to AXL, promoting its dimerization, autophosphorylation, and activation of downstream survival pathways, including the PI3K/AKT, MAPK/ERK, and NF-B pathways
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