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This synergy may be especially valuable for people who have struggled to see results with diet and exercise alone, as the combination addresses root metabolic imbalances rather than just calorie intake

This is especially true for individuals with lifestyle or dietary restrictions

Moreover, the natural flavonoid astilbin modulates the crosstalk between hepatic stellate cells and macrophages by activating the PXR receptor and inhibiting PINK1/Parkin-mediated mitophagy, improving the fibrotic microenvironment (175)

R., & Jaeschke, H

Clinical trial participants must obtain approval from their trial sponsor before travelling and follow any IMP accountability instructions provided