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GLP-1 medications don't directly deplete vitamins, but reduced food intake combined with slower digestion can lower levels of Vitamin B12, Vitamin D, iron, calcium, and fat-soluble vitamins
These medications slow gastric emptying to promote satiety and weight loss, but this mechanism can disrupt normal bowel function
Injection sites should be rotated with each weekly dose to prevent lipodystrophy, scarring, or persistent irritation at any single location
Similarly, hypervitaminosis D may lead to hypercalcemia, nephrocalcinosis, and vascular calcifications 60
She adds that these side effects are dose-dependent, meaning they can be more severe and pronounced with higher doses of medication