Most patients do regain weight after stopping semaglutide if they do not maintain the lifestyle habits developed during treatment
That dual action is what separates it from semaglutide and other single-receptor GLP-1 medications
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CNS Neurol Disord Drug Targets 2011;10:659669.ArticlePubMed 61
Novo Nordisks Peter Johannsen, MD, highlighted the biological signals observed and acknowledged the clinical limitations: subgroup analyses did not reveal meaningful benefit, and any potential responder group would be very small