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Functional studies revealed that activation of GLP-1R in the PVN reduces food intake (Larsen et al., 1997
Research on treatment breaks remains limited, but emerging data suggests that repeated cycles of treatment and discontinuation don't significantly diminish medication effectiveness
The weight and glycemic control were maintained for at least twelve months after the medication
10.1038/ncb2220 21 GuarnieriG.SitulinR.BioloG
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