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One study measuring levels of glutathione in 30 healthy people and 30 people with insomnia found that glutathione peroxidase was significantly lower in people with insomnia (13)

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HIF-1, as a transcriptional regulator plays a key role in the dysregulation of peroxisome proliferator-activated receptor alpha (PPAR) and Acyl-CoA, which ultimately hinders the production of FAO [37, 38]