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Whether the selectivity observed in animals translates perfectly to humans is assumed but not rigorously proven across dose ranges
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Glucagon-like peptide 1-based therapies for the treatment of type 2 diabetes mellitus
Short and medium-chain acetyl esters, formed in the mitochondria and peroxisomes, participate in the removal of organic acids [12]
Compared to placebo, GLP-1 receptor agonists reduced the risk of kidney failure by 16% and the worsening of kidney function by 22% (defined by a drop in estimated glomerular filtration ratea measure of how much blood the kidneys filter clean every minuteof at least 50%)
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