Rare but severe side effects include pancreatitis or thyroid tumors
IGF-1 DES has a very short half-life (20-30 minutes) and is thought to have a more localized effect, making it suitable for different research applications requiring short, targeted action
Vogel et al., 2020
What are the main side effects of retatrutide based on current trial data
The 30-minute post-dose window applies before other medicines, which is relevant for patients taking morning medication or drugs with a narrow therapeutic window
Looking ahead, the future of PDCs involves the development of PDCs based on humanized antibodies, 129 exploring stimuli-responsive drug release mechanisms, 130 employing computer-aided drug design, 131 exploring diverse receptors or antigens, 132 integrating with immunotherapies and gene therapies to address stability, off-target effects and resistance issues, 133,134 and advancing scalable manufacturing processes