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Stratified analyses showed no differences in the risk of SIS when prescribed GLP-1RA or SGLT-2i between participants with and without depression, anxiety or sleep disorders, between women and men, and between individuals in different obesity categories (ESM Fig

NAD+ Nicotinamide adenine dinucleotide (NAD+) is a fundamental molecule needed to regulate a broad spectrum of cellular processes in the human body

While proteins can contain hundreds or thousands of amino acids, peptides typically include between 2 to 50 , giving them the ability to act as precise signaling molecules in the body