Semaglutide can help to reduce appetite, leading to weight loss over time
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Thereafter, the observation of incretin activity after the inactivation of GIP suggested the existence of other molecules with an incretin effect
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Guevara-Aguirre J, Rosenbloom AL
The SURMOUNT and STEP trial programs have established semaglutide as the clinical gold standard for pharmacological weight management, with mean body weight reductions of 14.9% to 17.4% in phase 3 trials significantly exceeding those of competing agents