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No adverse fetal effects have been documented from normal therapeutic doses of hydroxocobalamin in human pregnancies
The authors reported that AOD-9604 stimulated lipolysis in isolated adipocytes and that chronic daily treatment in obese Zucker rats produced reductions in body weight gain of more than 50% relative to untreated controls over the treatment period, without effects on insulin sensitivity or IGF-1 levels [3]
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This protein has an effect on cellular senescence and apoptosis, and it interacts with other proteins and signaling pathways to regulate gene expression, affecting cellular responses to stress, DNA repair, and cell survival
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Mice tolerated the treatment well throughout the study period
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