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However, there is no scientific evidence supporting B12 supplementation for direct fat loss in individuals with normal B12 levels

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Every fat-metabolism, NAD+, SIRT1 and lean-mass effect described above is preclinical (rodent or cell) only and should be read as a hypothesis, not an established human benefit

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Preclinical studies indicate that NNMT knockdown or inhibition can protect against diet-induced weight gain and improve metabolic parameters without reducing food intake [5] [6]

[23] Your healthcare provider will determine the appropriate dosage and frequency for you