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For instance, chronic high H 2 O 2 levels can activate p38 continuously, inducing melanocytes to premature senescence (dysfunctional) and susceptible to apoptosis ( FIGURE 7 Vitiligo patients have a reduced mitophagy process in epidermal melanocytes (Lotti and DErme, 2014)

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doi:10.1111/j.1365-2982.2009.01436.x Elsenbruch S, Rosenberger C, Enck P, Forsting M, Schedlowski M, Gizewski ER

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(2017) investigated the bacterial inactivation after the simultaneous or sequential application of ELA and eugenol

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Proper use and dosage instructions must be strictly followed to reduce negative effects and increase efficacy

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