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doi: 10.1177/1934578X19890816 224 Revilla-MonsalveMAndrade-CettoAPalomino-GaribayMAWiedenfeldHIslas-AndradeS
These therapeutic approaches are currently regarded as experimental and off-label, and patients should be fully informed of the limited empirical support for their efficacy and safety in these contexts
Customize follow-up frequency to procedure severity and comorbidities
Within the dosing regimen (starting at a low dose and increasing the dose based on efficacy and tolerability), no dose adjustments are necessary
Due to accumulation of metabolic intermediates, impaired carnitine biosynthesis, reduced protein intake, and increased removal of carnitine through hemodialysis (HD), patients who undergo routine HD usually present with plasma carnitine insufficiency [54]
Plaintiffs allege the companies did not adequately disclose the risk that the drugs could severely slow stomach emptying, leaving patients and doctors unaware of the potential complication
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