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In humans, Menkes syndrome is a main manifestation of copper deficiency and causes serious neurological disorders (Danks et al., 1972

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Research has shown approximately 40% oral bioavailability in animal studies

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Management approaches include increasing fiber intake gradually (too much fiber at once worsens bloating), drinking at least 64 ounces of water daily, taking magnesium citrate (400-600mg at bedtime), and increasing physical activity