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Park JJH, Sharif B, Harari O, Dron L, Heath A, Meade M, et al
Other milder issues: Abdominal pain or dyspepsia (indigestion) can happen with either medication, though they are less common overall
Mean relative liver fat reduction was greater than 80% with retatrutide 8 mg and 12 mg, and 80% or more of participants on retatrutide 8 mg and 12 mg had a 70% or more relative reduction in liver fat
Sleep Improvement May Be a Factor Eczema and sleep disruption have a bidirectional relationship, with itch-driven sleep fragmentation worsening eczema severity through immune dysregulation, and poor sleep independently lowering itch threshold
It's important to note that GLP-1 secretion is also integrated with neural and hormonal signalling beyond direct nutrient sensing
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