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Data availability All data generated or analysed during this study are included in this published article [and its supplementary information files]

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Despite there being various techniques to encapsulate the drugs and increase encapsulation efficiency, the freeze-thaw cycling and reverse phase evaporation techniques are used extensively [135]

These findings highlight potential risks for patients undergoing surgery, especially concerning pulmonary aspiration during anesthesia

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Every dose below assumes a 5mg vial reconstituted with 2mL bacteriostatic water, giving a 2.5mg/mL concentration, measured with a standard 100-unit insulin syringe