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For complete thymosin beta-4, intravenous single doses of up to 1260 mg were well tolerated in healthy subjects, with no dose-limiting toxicity Ruff et al., 2010, and recombinant thymosin beta-4 showed no accumulation Wang et al., 2021
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Intravenous administration might be better in some cases
Levels of carnitines and amino acids at birth in neonates at risk to develop T1D Compared with controls, significantly low levels of total carnitine, free carnitine and acyl-carnitines were found in neonates who would develop T1D later in their childhood
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Obesity and depression: its prevalence and influence as a prognostic factor: a systematic review
