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In addition, OPL can increase the secretion of NO, iNOS and POD by regulating miR-1338, promote cell phagocytosis and migration, increase the expression of TLR4, MyD88, IKK and NF-B mRNA and protein, inhibit cell apoptosis and ROS secretion, thereby improving Kupffer cell activity (72)

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3,4 Common side effects associated with the use of this medication include symptoms of fatigue as well as sleep disturbances including insomnia