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doi: 10.1111/pcmr.12365

It is advisable to start with a lower dosage and then add as time goes by

Given its potent redox capabilities, and its high intracellular concentration and widespread distribution, its role as a potent defense mechanism against oxidative and electrophilic stress is well-established

PubMed Central , Grub, Jessica, et al

While its topical safety record is strong, its systemic safety and efficacy for treating medical conditions have not been established through comprehensive, large-scale, independent Phase 3 human trials

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