As a GIP receptor agonist, it enhances insulin secretion and may improve insulin sensitivity
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Akhter N, Ahmad S, Alzahrani FA, Dar SA, Wahid M, Haque S, et al
[29] [30] While these side effect profiles do not directly overlap, patients experiencing significant gastrointestinal symptoms from tirzepatide may find niacin's additional gastrointestinal effects poorly tolerated
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