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Molecules 24 , 3111 (2019)
The inhibition of mTORC1 signaling by cystine starvation demonstrated that regulation of this pathway is not limited to essential amino acids 9,10,11,12 , but is also regulated by cysteine availability (Fig
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Key loci include immune-modifying genes such as human leukocyte antigens (HLA class I and II) and cytotoxic T-lymphocyte-associated protein 4 (CTLA-4)
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