Inflammation Inflammation Inflammatory signals can activate melanin production pathways
Especially important is the trigger of limbic system dysfunction, vagal nerve dysfunction - if these are not addressed first it is very difficult to help patients
Figure 6 Zinc, as a cofactor for the antioxidant enzymes such as superoxide dismutase (SOD1) and catalase (CAT), may be helpful in reducing oxidative stress from insulin resistance
However, in contrast to the general trend of reduced BChE in depression, Modai et al
108 The role of HIF in IR is controversial
Early lab and animal studies suggest improved absorption and cellular uptake compared to standard ALA.58 However, human studies are limited, so its clinical superiority remains unproven