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Moreover, it was established that the tested doses (30 or 60 g/kg) were well-tolerated [3]

Those following a regular exercise plan and aiming to optimize performance

The interplay between the somatotropic axis and sleep regulation has been extensively documented in both preclinical and clinical studies, demonstrating the integral role of growth hormonereleasing hormone (GHRH), somatostatin, GH itself, insulin-like growth factor-I (IGF-I), synthetic GH secretagogues, and ghrelin in modulating sleep architecture ( In normal individuals, sleep-onset GH secretion appears to be primarily regulated by GHRH stimulation during a period of relative somatostatin withdrawal

Schaffer et al

It is important to understand that GLP-1 medications require dose titration starting at a lower dose and gradually increasing over several weeks or months

PLoS Genet