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Neither compound significantly alters the other's clearance or plasma concentration
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In addition to decreasing the fluidity of the platelet membrane and promoting platelet aggregation, coagulation factors and PAI-1 (plasminogen activator inhibitor-1) will also increase under the condition of hyperglycemia, breaking the balance of coagulation and fibrinolysis and promoting thrombosis
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Over the years, it has become one of the most frequently discussed compounds in peptide research due to the wide range of biological systems in which it has been investigated
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