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doi: 10.1016/j.fct.2010.04.022
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Spadoni, S
FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization
Given that mitochondrial one-carbon metabolism is very important for cancer progression, the entry of serine into the mitochondria is a critical step in the generation of one-carbon units
Typical requirements include a documented BMI of 30 or higher (or 27 or higher with a related condition like type 2 diabetes, high blood pressure, or sleep apnea), and sometimes evidence that you have already tried and not succeeded with other weight management approaches
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