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Upregulated Hexokinase 2 expression induces the apoptosis of dopaminergic neurons by promoting lactate production in Parkinsons disease

PMID: 17015261

This shows that hypertension leads to iron overload in the brain, and iron overload increases OS and lipid peroxidation, thereby causing ferroptosis (Yang et al., 2020) in neurons and ultimately leading to brain injury (Figure 2)

Second, it has been shown that the oxidation of dihydroriboflavin, the reduced riboflavin, forming oxidized riboflavin can deactivate lipid peroxides, emphasizing the independent antioxidant property of riboflavin (33)

Caspase and bid involvement in Clostridium difficile toxin A-induced apoptosis and modulation of toxin A effects by glutamine and alanyl-glutamine in vivo and in vitro

Peer-reviewed studies on GHK-Cu Maquart FX, Pickart L, Laurent M, et al