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Hosono, K

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The Diabetes Prevention Program demonstrated that intensive lifestyle intervention can produce 5-7% weight loss and reduce diabetes risk, though maintaining this weight loss long-term proves challenging for many individuals without ongoing support

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Volpato S, Bianchi L, Cherubini A, Landi F, Maggio M, Savino E, Bandinelli S, Ceda GP, Guralnik JM, Zuliani G, et al

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The Journal of clinical investigation , 132 (19), e152341.

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Endocrinology Targeting the central melanocortin system for the treatment of metabolic disorders 2023 DOI: 10.1038/s41574-023-00855-y PMID: 37365323 Sweeney P, Gimenez LE, Hernandez CC, et al

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